Genomic Alterations in Breast Cancer Patients in Betel Quid and Non Betel Quid Chewers

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Genomic Alterations in Breast Cancer Patients in Betel Quid and Non Betel Quid Chewers

Betel Quid (BQ) chewing independently contributes to oral, hepatic and esophageal carcinomas. Strong association of breast cancer risk with BQ chewing in Northeast Indian population has been reported where this habit is prodigal. We investigated genomic alterations in breast cancer patients with and without BQ chewing exposure. Twenty six BQ chewers (BQC) and 17 non BQ chewer (NBQC) breast canc...

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Intention to quit betel quid: a comparison of betel quid chewers and cigarette smokers.

BACKGROUND Despite the global significance of betel quid chewing and the associated health risks, there have been no studies assessing chewers' intention to quit. Given the difficulties associated with quitting betel quid and the serious health consequences of chewing, it is important for researchers to develop interventions aimed at helping chewers quit. Betel quid chewers experience similar p...

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Altered Brain Functional Connectivity in Betel Quid-Dependent Chewers

Background Betel quid (BQ) is a common psychoactive substance worldwide with particularly high usage in many Asian countries. This study aimed to explore the effect of BQ use on functional connectivity by comparing global functional brain networks and their subset between BQ chewers and healthy controls (HCs). Methods Resting-state functional magnetic resonance imaging (fMRI) was obtained fro...

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Salivary Flow Rates in Paan “ Tobacco - Betel - Lime Quid ” Chewers

Objectives: To study whether ingredients of Paan especially tobacco has got any untoward effects on secretion of saliva or otherwise. Material and Methods: Subjects of the study were divided into paan-chewers and non-chewers as controls. Each group contained 20 healthy male adults. The saliva of each subject was collected under resting condition and following stimulation by crude nicotine and c...

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Epidemiology of betel quid usage.

Betel quid chewing is an ancient practice common in many countries of Asia and among migrated communities in Africa, Europe and North America. It enjoys complete social acceptance in many societies and is also popular among women. In its most basic form, betel quid consists of betel leaf (Piper betel), areca nut, the main psychoactive ingredient, and slaked lime (calcium hydroxide). Areca nut i...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2012

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0043789